Asymmetric Reactions of Aldehydes, Ketones, and Acetals

To achieve asymmetric allylation with allylsilanes, the control of absolute configuration by use of chiral auxiliaries was extensively studied in the nineteen-eighties. Recently, much effort has been directed toward the use of optically active a-chiral allylsilanes and catalytic asymmetric allylation using chiral Lewis adds and bases. 

Allylsilanes bearing a chiral ligand on the silicon atom can be used for asym- 

Fleming et al. have achieved the preparation of enantiomerically pure allyltri- 

TMS-acrylamide derived from homochiral camphor sultam as the key step [390]. 

They have also succeeded in highly enantioselective synthesis of allenyltrimethylsi- 

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