Astrocytes neurotransmitter uptake into

The properties of classical neuro transmitters, as described for ACh and NE, can be applied with some variations to numerous other substances which have subsequently been determined to act as neurotransmitters. For example, in the case of amino acid transmitters such as GABA or glutamate, we would note that much of the released neuro transmitter is cleared from synapses by high affinity uptake into glial cells (astrocytes), in addition to nerve terminals. Peptide neurotransmitters, such as one of the endor-... 

The action of the neurotransmitter is terminated through reuptake into the presynaptic terminal, uptake into glial cells, diffusion away from the synapse, or enzymatic inactivation. The enzymatic inactivation may occur in the postsynaptic terminal, the presynaptic terminal or an adjacent astrocyte microglia cell, or in endothelial cells in the brain capillaries. 

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