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Astramembrannin

Antiinflammatory effects of astramembrannin I (astragaloside IV), isolated from A. membranaceus, were demonstrated in rats. This compound inhibited the increase of vascular permeability induced by serotonin or histamine. Oral administration of astramembrannin I caused a dose dependent reduction in carrageenan-induced edema of the hind paw of rats [15]. [Pg.220]

Among the many pharmacological properties of Astragalus, those on the cardiovascular system are of special interest. Astramembrannin I (astragaloside IV), produced a hypotensive effect after i.v. administration to anaesthesized cats and rats [15]. [Pg.220]

Several other activities are reported for Astragalus spp. the cycloartane saponins from A. sieversienus show an hypocholesterolemic action [219], while astramembrannin I, 87, and astrasieversianin I, 92 produce antileukocytopenic and anti-stress effects in mice [319]. Aqueous extract of A. membranaceus root causes significant stimulation of melanocyte proliferation using the sulphorhodamine B (SRB) test. This result supports the use of these extracts in traditional treatments of vitiligo [191]. [Pg.483]

See other pages where Astramembrannin is mentioned: [Pg.1037]    [Pg.457]    [Pg.457]    [Pg.480]    [Pg.481]    [Pg.481]    [Pg.482]    [Pg.457]    [Pg.457]    [Pg.480]    [Pg.481]    [Pg.481]    [Pg.482]    [Pg.56]    [Pg.1037]    [Pg.457]    [Pg.457]    [Pg.480]    [Pg.481]    [Pg.481]    [Pg.482]    [Pg.457]    [Pg.457]    [Pg.480]    [Pg.481]    [Pg.481]    [Pg.482]    [Pg.56]   
See also in sourсe #XX -- [ Pg.480 , Pg.481 ]

See also in sourсe #XX -- [ Pg.480 , Pg.481 ]



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Triterpenoid saponins astramembrannin

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