Association constants for binding

Antigen Injected (mg) Average Intrinsic Association Constants for Binding of c-DNP-Lysine to Anti-DNP Antibodies ... 

Association Constants for Binding of Various Pyrimidines to Zn2(DPD) (13) in Dichloromethane... 

A useful approach for characterizing the influence of various factors on E° is to consider the relative effects on the stability of the oxidized and reduced states. Interactions that preferentially stabilize the reduced state (or preferentially destabilize the oxidized state) will increase E°, whereas the converse situation will be reflected by a decrease in E°. Formally, if the reduced and oxidized forms of a redox cofactor have association constants for binding the protein of and Ko, respectively, then the observed midpoint potential, E°, is related to the intrinsic potential of the free cofactor, E°, by the expression... 

Figure 11 Structure of a tetralactam host 32 bound to p-benzoquinone 33 and association constants for binding with guests 33-36.

Whether or not the group at C(3 ) of the cephalosporin [2] is expelled or not makes little difference to the rate enhancement brought about by the metal ion. The 3-methyl derivative, has a similar association constant for binding of copper(II) ion to that for cephaloridine [11] (X = CHj-pyridi-nium) (Table 7). The rate enhancement brought about by copper(II) ion is the same within a factor of 2 (Gensmantel et al., 1980). 

To shed light onto the evident Ceo encapsulation within the porphyrin cyclic-dimer a variety of metal centers were probed (i.e., Co(II), Rh(III), Ni(II), Cu(II), Ag(II) and Zn(II)). Based on metal-to-fullerene-charge-transfer interactions, the Rh(III) led to an unprecedentedly high association constant - for binding Cgo - of 2.4 x lO NT. Inferior rates were derived for the remaining metal centers, with values typically on the order of 10 M. ... 

Analogs For Multisubstrate Reactions - N-(Phosphonacetyl)-L-aspartate (32) incorporates features of both substrates of the enzyme aspartate transcarbamylase (33), although it does not contain a tetrahedral functional group analogous to the tetrahedral-like transition state that is e q>ected for The association constant for binding of... 

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