Arylthio 2- -amino

The ligands halogeno, alkoxy (or aryloxy), alkylthio (or arylthio), amino, phosphide and NO that are all 1-electron ligands can also be 3-electron LX ligands when the metal is electron-deficient i.e. has less than 18 valence electrons vide supra)... 

Jap-KIingermarm reactions, 4, 301 oxidation, 4, 299 reactions, 4, 299 synthesis, 4, 362 tautomerism, 4, 38, 200 Indole, 5-amino-synthesis, 4, 341 Indole, C-amino-oxidation, 4, 299 tautomerism, 4, 298 Indole, 3-(2-aminobutyl)-as antidepressant, 4, 371 Indole, (2-aminoethyl)-synthesis, 4, 278 Indole, 3-(2-aminoethyl)-synthesis, 4, 337 Indole, aminomethyl-reactions, 4, 71 Indole, 4-aminomethyl-synthesis, 4, 150 Indole, (aminovinyl)-synthesis, 4, 286 Indole, 1-aroyl-oxidation, 4, 57 oxidative dimerization catalysis by Pd(II) salts, 4, 252 Indole, 1-aroyloxy-rearrangement, 4, 244 Indole, 2-aryl-nitration, 4, 211 nitrosation, 4, 210 synthesis, 4, 324 Indole, 3-(arylazo)-rearrangement, 4, 301 Indole, 3-(arylthio)-synthesis, 4, 368 Indole, 3-azophenyl-nitration, 4, 49 Indole, 1-benzenesulfonyl-by lithiation, 4, 238 Indole, 1-benzoyl photosensitized reactions with methyl acrylate, 4, 268 Indole, 3-benzoyl-l,2-dimethyl-reactions... 

Pterin, 4-amino — see Folic acid, 4-amino-4-deoxy-Pterin, 6-amino-structure, 3, 276 Pterin, 7-amino-structure, 3, 276 Pterin, 6-arylthio-reactivity, 3, 299 Pterin, 6-(l-carboxyethoxy)-synthesis, 3, 309 Pterin, 6-carboxy-7-hydroxy-properties, 3, 277 Pterin, 7-carboxy-6-hydroxy-properties, 3, 277 Pterin, 6-chloro-nucleophilic substitution, 3, 292 synthesis, 3, 290... 

Pyridazine, 4-amino-5-formyl-3,6-dimorpholino-synthesis, 3, 346 Pyridazine, 4-amino-3-halo-reaction with potassium amide, 3, 29 Pyridazine, aryl-synthesis, 3, 28 Pyridazine, arylthio-synthesis, 3, 27 Pyridazine, 3-azido-... 

The 0X0 group facilitates reaction relative to H, CH3, or NH2 substituents on pyrimidines in the displacement of mercapto, arylthio, or amino groups by amines. The 2-thioxo group is reactive toward... 

Jackson and coworkers have used a new approach to the synthesis of fi-hydtoxy-ct-amino acids using farylthio nitrooxiranes. c-Jsopropylideneglyceraldehyde is converted into the corresponding 1-arylthio-l-nitroalkene, which is a key material for stereoselective synthesis of fi,Y-dihydroxyamino acids fScheme 4.6. The key step is stereoselective nucleophilic epoxlda-donof the Tarylthio-Tnltroalkene. Sy)i and ruin epoxides are selecdvely obtained by appropriate choice of epoxidadon reagent." ... 

An amino group and an arylthio group can be added to a double bond by treatment with a sulfenanilide (PhSNHAr) in the presence of BFs-etherate. The addition is... 

The structures of some stable stannylenes, such as several amino-, " alkoxy-, and arylthio-substituted intermediates, have been revealed by X-ray crystallography. They are monomeric crystals and the tin atom has the coordination number 2. The divalent tin in such compounds is stabilized by the effects of electronegativity of the ligand atoms and by the donation of the lone-pair electrons to the vacant 5p orbital of the tin. Although the first monomeric dialkyl- and diaryl- stannylenes in... 

Treatment of the enol tosylate obtained with amines led to the formation of / -amino-a-fluoro acrylaldehydes (Eq. 90) when bifunctional nitrogen nucleophiles were used, pyrazoles and pyrimidines were obtained [267]. More recently the reaction has been used to prepare the alkyl- or arylthio congeners [268]. 

A variety of substituted 3-aminobenzo[6]thiophenes have been obtained by ring closure reactions of nitriles (equation 57). Various o -cyanophenylthioacetyl derivatives, when treated with base, yield the 3-amino derivatives (Section 3.15.2.2.3). The benzonitriles may be obtained by displacement of the o-nitro group from o -nitrobenzonitriles (74JOC3440). 2-Arylthio-l-chloroenamines are cyclized to 3 -dialkylaminobenzo[6]thiophenes in the presence of Lewis acid catalysts (equation 58). The 1 -chloroenamines may be prepared from t-amides or ynamines <8lH(15)l 179>. 

The use of MPc complexes as electrocatalysts for the detection of analytes relies on the formation of modified electrodes. Thiol, alkylthio, or arylthio substituted MPc complexes readily form self-assembled monolayers (SAMs) on gold. Amino substituted MPc complexes can easily be electropolymerized onto electrodes. Direct adsorption of the monomer onto electrodes (especially carbon electrodes) also occurs. The modified electrodes are then employed for detection of analytes ranging from neurotransmitters, thiols, phenols, and other biologically and environmentally important molecules. 

Amino-l,2-benzisothiazoles such as 54 have been claimed22 to possess antiinflammatory, analgesic, and hypotensive properties, while 3-dialkylamino-l,2-benzisothiazoles16 and 3-aryloxy- or 3-arylthio-l,2-benzisothiazoles (55)23 have useful antimycotic activity. 

Condensation of 2-amino-5-bromomethyl-3-cyanopyrazine 1-oxides with the appropriate substituted amine afforded a series of 2-amino-5-([(aryl and aralkyl)-amino]methyl -3-cyanopyrazine 1-oxides (1040), and with p-chlorophenol and arylthiols gave 2-amino-5-[(p-chlorophenoxy)methyl]-3-cyanopyrazine 1-oxide and 2-amino-5[(arylthio)methyl]-3-cyanopyrazine 1-oxides (1041). 

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