Arylphosphonic acid derivatives

Third, arylphosphonic acid derivatives have been made by or-ganometallic reactions, such as the reaction of C6H5MgBr with (C2H50)2P0C1 or of phcnyllithium with phosphorodipiperididic chloride.9"11... 

Arylphosphonic acid derivatives, 58, 137 Arylphosphonic dichlorides, 58, 136 Aryltetrachlorophosphoranes, 58, 137 L-Asparagine, carbobenzoxy-, 56, 89 L-Asparagine, NJ-(tnfluoroacetyl)- 56, 125 L ASPARAGINYL-L-LEUCINE, CARBOBENZOXY-,METHYL ESTER, 56, 88 Z-Asp Gly-OEt, 56, 93 (l-Azido-3,3-dimethoxy-l-propenyl)ben-zene, 57, 84... 

Other methods for synthesis of arylphosphonic acids or their derivatives fall into four main categories. First, many aromatic compounds react with PC13 under catalysis by A1C13 to form aryldichlorophosphines (ArPCl2).9a n These add chlorine to form... 

Moskva, V.V., Maikova, A.I., and Razumov, A.I., Phosphonic and phosphonous acid derivatives. Part 64. Reaction of phosphites and arylphosphonates with orthoacetic ester, Zh. Obshch. Khim., 39, 2451, 1969 J. Gen. Chem. (Engl. Transl.), 39, 2391, 1969. 

In both cases, the NHMe group impedes the substantiation of the relative importance of resonance effect of these substituents as established in section II.B, even though the inductive mechanism becomes significant. An identical a g a, sequence of these groups was obtained from the ionization constants of the corresponding meta derivatives of arylphosphonic acids . The Hammett equation has also been successfully used to calculate a a value for the resonance inhibited />-NMea group In most cases Umeta is consistently less negative than Opara-... 

At this juncture, it may be noted that aryltetrachlorophosphoranes have been used to provide a wide range of derivatives of arylphosphonic and diarylphosphinic acids, as... 

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