Aryldialkyl phosphatases

As anhydrides, such compounds are subject to spontaneous hydrolysis, which may contribute to detoxification [160]. Thus, soman hydrolysis at pH 7.5 and 37° occurs with a rate constant of 0.003 - 0.004 min-1 and an activation energy of ca. 55 kJ mol 1 [161]. However, most of the published data refer to enzymatic hydrolysis. Enzymes hydrolyzing P-X anhydride bonds are now known as organophosphorus acid anhydrolases (OPA anhydrolases) classified as EC 3.1.8.2 (also known as diisopropyl-fluorophosphatase, DFPase, tabunase, somanase), an activity related to EC 3.1.8.1 (aryldialkyl-phosphatase, paraoxonase, A-esterase) and formerly classified as EC 3.8.2.1 [64] [65] [69], Much public information on these enzymes can be found in [106],... 

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