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Arthropods pharmacologically active

The 1-phenylpyrazole core has been shown to bestow pharmacological activity in a number of areas in the pharmaceutical and agrochemical industries. In the latter field, select examples of biological activities include insecticidal, miticidal, and herbicidal. More specifically, 1-phenylpyrazoles with alkyl, acyl, thioalkyl, or cyano substituents at the 4-position exhibit potent insecticidal activity. In particular, 5-amino-I-(2,6-dichloro-4-trifluoro-methylphenyl)-4-trifluoromethanesulfinyl-l//-pyrazole-3-carbonitrile (Fipronil ) is one of the most commercially successful insecticides. In fleas, ticks, and other arthropods, it acts as a gamma-aminobutyric acid (GABA)-gated... [Pg.118]

Arthropod saliva contains pharmacologically active molecules... [Pg.350]

Pharmacologically active molecules in saliva of blood-feeding arthropods and released by tissue dwelling species are essential for their survival 32, 33). Likewise, blood-feeders and myiasis larvae have multiple ways to counteract host coagulation pathways, platelet aggregation, and vasoconstriction 32, 34, 35, 28, 36, 29, 37). [Pg.351]


See other pages where Arthropods pharmacologically active is mentioned: [Pg.44]    [Pg.348]    [Pg.351]    [Pg.356]    [Pg.368]    [Pg.280]    [Pg.114]    [Pg.268]    [Pg.62]    [Pg.97]   


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Arthropods

Pharmacologic activity

Pharmacologically active

Pharmacology activity

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