Hypertrophic arthritis

Episodic or chronic arthritis and hypertrophic pulmonary osteoarthropathy may also occur due to immune complex formation in response to chronic inflammation.11 Digital clubbing is commonly observed and is a marker for hypoxia. 

Short courses of non-steroidal anti-inflammatory drugs (NSAIDs) can be used to treat CF-related arthritis and hypertrophic pulmonary osteoarthropathy.5 The impact on neutrophil recruitment in the lung with long-term NSAID therapy at lower analgesic doses is unknown. 

Arthritis may occur in CF and can take one of several forms. The arthritis may be either mono- or polyarticular and usually is nondestructive. An episodic form is most common and may be due to immune complexes formed in response to the chronic pulmonary infections. Hypertrophic osteoarthropathy occurs in CF, as it does in association with other pulmonary diseases. The incidence of arthritis may be increasing as median survival age increases. Osteopenia and osteoporosis also occur more frequently in adults with CF. The causes of the resulting bone deminerahzation are multifactorial and include vitamin D malabsorption, decreased vitamin D conversion (via sunlight), delayed puberty and endocrine development, poor nutrition, limited physical activity, and chronic acidosis. 

Osteoarthritis (degenerative joint disease, or hypertrophic arthritis)... 

OSTEOARTHRITIS (DEGENERATIVE JOINT DISEASE, OR HYPERTROPHIC ARTHRITIS). Osteoarthritis, which is the most common type of arthritis, results from the wear and tear on the joints. Most persons over 50 years of age have osteoarthritis to some degree for this reason it is often called old-age rheumatism. However, it... 

Fig. 10.41 a,b. Hypertrophic tenosynovitis of the extensor carpi ulnaris in a patient with rheumatoid arthritis, a Short-axis and b long-axis 12-5 MHz US images of the extensor carpi ulnaris tendon (ecu) reveal hypoechoic synovial pannus (arrowheads) which causes abnormal distention of the synovial sheath. The extensor carpi ulnaris is displaced anteriorly because of loosening of the retinaculum. Note the pannus filling the distal radioulnar joint cavity (arrow)... 

Hypertrophic tenosynovitis are more commonly an expression of systemic arthritides, such as rheumatoid arthritis or psoriatic arthritis, but they can also be encountered as the end result of chronic... 

US has also proved an effective means of identifying tendon changes related to serous and hypertrophic tenosynovitis (Fig. 16.60) (Miller et al. 1996 Chen and Liang 1997 Premkumar et al. 2002). These changes occur commonly in patients affected by systemic arthritis. Instability of the tibialis posterior tendon, including subluxation and dislocation in... 

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