Arenediazonium salts substituted benzene synthesis using

Gomberg-Bachmann biphenyl synthesis. Reaction of stable arenediazonium tet-rafluoroborates or hexafluorophosphates in an aromatic solvent with potassium acetate (2 equiv.) and a phase-transfer catalyst results in biar Is in high yield. Crown ethers, Aliquat 336, and tetrabutylammonium hydrogen sulfate arc all effective catalysts. The reaction is useful for synthesis of unsymmetrical biaryls. The ortho-isomer predominates in reactions with a monosubstituted benzene. The most selective method is to couple a substituted arenediazonium salt with a symmetrical arene. 

Synthesis of Substituted Benzenes Using Arenediazonium Salts... 

THE SYNTHESIS OF SUBSTITUTED BENZENES USING ARENEDIAZONIUM SALTS... 

---

See also in sourсe #XX -- [ , , ]

---