Applications of Models and Flow Sheets in Bioseparation Economics

APPLICATIONS OF MODELS AND FLOW SHEETS IN BIOSEPARATION ECONOMICS 

Datar13 indicates that the total manufacturing cost of a bioprocess may be given by  

The total manufacturing cost includes administration, research and development, distribution, and selling. Here RM represents the costs of the raw materials FCI is the fixed capital investment OL is the cost of operating labor E is energy costs Z is the step or overall yield and a, /3, y, and 8 are coefficients that must be determined for a specific situation. 

The next two examples pursue this line of thought further wherein we analyze a computer-aided process of human insulin production.15 This is then followed by an analysis of process simulation of heparinase I production from E. coli.5 

Example 5 An Economic Analysis of Biosynthetic Human Insulin Production15 

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