Apocamphane-1-carboxylic acid decarboxylation

Ketopinic acid is of interest as a /3-keto acid which fails to decarboxylate readily. It may be converted to apocamphane-1-carboxylic acid. ... 

Decarboxylation of alkanoic acids means of LTA in benzene as solvent is hindered by die formation of all lbenzenes as by-products. This side reaction is especially pronounced widi radicals derived from primary acids or odier acids from which the radical is not easily oxidized LTA. In some cases, such as that of apocamphane-l-carboxylic acid (equation 54), good yields of alkylbenzene can be obtained. Intramolecular versions of this reaction in which the radical cyclizes onto an aromatic nucleus at the appropriate position in the chain have also been observed. 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ ]

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