Apical functionalization approach

Cavitand-based Dimeric Coordination Cages 7.2.2.1 The Apical Functionalization Approach... 

There are several approaches to evaluate lung toxicity in vitro, which aim on epithelial function, like transport, apical surface liquid homeostasis, and barrier function, rather than on cellular function, like inflammation, metabolism, or cell viability. Most of these approaches disturb the air-liquid interface. It is affirmed that changes in airway liquid surface volume affects transepithelial ion transport [5] and impacts pharmacological properties at least of ENaC [89],... 

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