Anxiety neurobiology

Marsden, CA, Bickerdike, M, Cadogen, A-K, Wright, I, Rex, A and Fink, H (1993) Serotonergic mechanisms and animal models of anxiety. In Anxiety, Neurobiology, Clinic and Therapeutic Perspectives (Eds Hamon, M, Oilat, H and Thiebot, M-H), John Libbey Eurotext Ltd, 232, pp. 75-82. 

There are two main approaches to research into anxiety. The first is to establish experimental models of anxiety in animals and humans in order to discover its neurobiological basis. The second is to investigate the actions of anti-anxiety drugs in the brain in the hope that this will give some clues to the cause(s) of anxiety. This chapter will discuss evidence from both these lines of research. 

CHAPTER 55 Neurobiology of Severe Mood and Anxiety Disorders... 

It is hoped that our ever-expanding knowledge of the neurobiology of anxiety and anxiety disorders will yield entirely new pharmacological approaches to the treatment of these disorders. Despite some concerns with their... 

Heim, C. and Nemeroff, C. B. The role of childhood trauma in the neurobiology of mood and anxiety disorders preclinical and clinical studies. Biol. Psych. 49 1023-1039, 2001. 

Charney, D. S. and Drevets, W. C. The neurobiological basis of anxiety disorders. In Neuropsychopharmacology the Fifth Generation of Progress. Ed. Nemeroff, C. Philadelphia Lippincott Williams Wilkins, 2002, pp901-930. 

Charney, D. S. and Bremner, j. D. The neurobiology of anxiety disorders. In Neurobiology of Mental Illness. Ed Bunney, B. S. New York Oxford University Press, 1999, pp494-517. 

Eison MS. (1990). Serotonin a common neurobiologic substrate in anxiety and depression. J Clin Psychopharmacol. 10(3) SuppI 26S-30S. 

Paul SM. (1988). Anxiety and depression a common neurobiological substrate J Clin Psychiatry. 49(suppl) 13-16. 

Ferre P, Fernandez-Teruel, Escorihuela RM, DriscoU P, Corda MG, Giorgo O, Tabena A (1995) Behavior of the Roman/Verh high- and low-avoidance rat lines in anxiety-tests relationship with defecation and self-grooming. Physiol Behav 58 1209-1213 FUe SE (1995) Animal models of different anxiety states. In Biggio G, Sanna E, Costa E (eds) GABAa receptors and anxiety from neurobiology to treatment. Raven Press, New York, pp 93-113... 

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