Antithrombogenic polyurethane surface

In 1994, Ryu et al. [85] immobilized EFE to polyurethane using maleic anhydride methylvinyl ether copolymer (MAMEC) as an enzyme carrier. The EFE-immobilized polyurethane surface was highly antithrombogenic and had potential for reducing surface induced thrombus. 

A new material with good antithrombogenic properties, suitable as biomedical material which assures the endothelialization of the inner surface of a polyurethane tube to imitate the inner wall of a natural blood vessel has been synthesized by blending PVA with polycarbonate urethane)(PCU) [229],... 

As for the effect of anionic group, there are a number of reports dealing with the antithrombogenic behavior of sulfonate-modified surfaces of segmented polyurethane (SPU). An interesting feature of the adsorptive behavior of fibrinogen on these material surfaces will be discussed in Sect. 4.1. 

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