Antiretroviral Therapy When and What to Start

Initiating Antiretroviral Therapy When and What to Start 

Based on data from clinical trials, either an NNRTI-based or Pl-based regimen should be offered to andretroviral-naiVe patients for whom therapy is indicated. The preferred NNRTI-based regimen includes efavirenz and tw o NNRTIs either lamivudine or emh icitabine plus zidovudine or tenofovir. 

Generic/hade name (abbreviation) How supplied Usual adult dose Major adverse effects CSF/IC g 

Fosampienavir/Lexiva (f-APV) VOOmg tablets 700mg b.i.d. or 1400mg q.d. with ritonavh GI hitolerance, rash - 

Nelfmavh/Vhacept (NFV) 250mg tablets 750mg t.i.d. or 1250mg b.i.d. Diairhea, metabohc comphcadons 4.3 

Atazanavir/Reyataz (ATV) 100, 150, or 200mg capsules 400 mg q.d. or 300 mg q.d. with ritonavir when used with TDF or EFV Hyperbilirubinemia, atrio-ventricular block 0.02 

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