Antimicrobial activity silane

Gottenbosa B, Henny C, van der Meia, Klatterb F, Nieuwenhuisb P, and Busscher HJ. In vitro and in vivo antimicrobial activity of covalently coupled quaternary ammonium silane coatings on silicone rubber. Biomaterials, 2002, 23, 1417-1423. 

Gottenbos, Bart, van der Mei, Henny, Klatter, Flip, nieuwenhiiis, Paul and Henk J. Busscher. In vitro and In vivo Antimicrobial Activity of Covalently Coupled Quaternary Ammonium Silane Coatings on Silicone Rubbei, BioMaterials, March 2002 1417-23. 

The ability to create essentially irreversible polymeric coatings of cationic silanes on surfaces and the ability of these modified surfaces to kill and/or control microorganisms has been demonstrated in laboratory and real world situations. A large number of microbological techniques have been found useful in determining the antimicrobial activity of a wide variety of surfaces with polymeric antimicrobials. This has provided considerable insight into the mode of antimicrobial action of these compounds. 

Shao, H., Meng, W. D. Qing, F. L. (2004). Synthesis and surface antimicrobial activity of a novel perfluorooctylated quaternary ammonium silane coupling agent. Journal of Fluorine Chemistry, 125, 721-724. 

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