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Antihypertensives Neuroleptics

The benzazepines are not as important pharmacologically as their more famous relatives the benzodiazepines. However, 3-aryl-2-(piperazin-l-yl)-5//-l-benzazepines, e.g. 14, and 17/-3-benzazepin-2-amines 15 possess neuroleptic activity,60 and antihypertensive activity,45 61 respectively. [Pg.211]

Dopamine antagonist activity is the hallmark of classical neuroleptics. The antihypertensive agents, reserpine (obsolete) and a-methyldopa, deplete neuronal stores of the amine. A common adverse effect of dopamine antagonists or depletors is parkinsonism. [Pg.114]

The Rauwolfla alkaloid reserpine was originally used as a neuroleptic/antipsychotic agent. It was then discovered to be an effective antihypertensive agent. Reserpine causes depletion of the noradrenaline stores in peripheral postganglionic sympathetic neurons. In addition it causes depletion of noradrenalin in central nervous structures involved in the regulation of blood pressure. [Pg.327]

Reserpine is a neuroleptic and an antihypertensive medication obtained from Rauwolfia... [Pg.515]

Phenothiazine neuroleptics (e.g. chlorpromazine, thioridazine) + vasodilators and antihypertensive drugs —> increased hypotensive effects due to increased peripheral vasodilation. [Pg.461]

Antibacterial Neuroleptic agent Antihypertensive Antilice/Antiscabies Nondepolarizing muscle-relaxing agent Antibiotic... [Pg.592]

D-TR (4), 5HT-TR (40 nM), [T synaptic 5HT antiaddictive, anticonvulsant, CNS stimulant, hallucinogen] VMA-TR [antihypotensive, antipsychotic, tranquillizer] MA-TR, VM-TR VMAT1 (adrenal chromaffin granule), VMAT2 (brain, adrenal), I.-type Ca2+ CH-dependent NE release (6) (MDR-TR) [antihypertensive, antipsychotic, carcinogen, tranquillizer, neuroleptic CNS antidepressant] GABA-TR... [Pg.241]

In general, concurrent use of neuroleptic and antihypertensive drugs merits close patient monitoring (632). [Pg.234]

Indeed, they are known for their anxiolytic, cardiovascular, analgesic, antihypertensive, and neuroleptic among other activities. These heteroclyclic skeleton forms the core structure of several drug molecules like zolpidem used in the treatment of insomnia, alpidem, an anxiolytic agent, olprinone for the treatment of acute heart failure, minodronic acid useful for the treatment of osteoporosis, and zolimidine used for the treatment of peptic ulcer. Besides, imidazo[l,2-a] pyridines and pyrimidines are also attractive due to their physicochemical properties such as fluorescent activity [128]. [Pg.451]


See other pages where Antihypertensives Neuroleptics is mentioned: [Pg.596]    [Pg.310]    [Pg.596]    [Pg.310]    [Pg.426]    [Pg.19]    [Pg.181]    [Pg.267]    [Pg.269]    [Pg.276]    [Pg.301]    [Pg.312]    [Pg.202]    [Pg.181]    [Pg.269]    [Pg.276]    [Pg.301]    [Pg.302]    [Pg.312]    [Pg.205]    [Pg.274]    [Pg.187]    [Pg.285]    [Pg.21]    [Pg.210]    [Pg.100]    [Pg.240]    [Pg.512]    [Pg.246]    [Pg.276]    [Pg.302]    [Pg.874]    [Pg.100]    [Pg.303]   
See also in sourсe #XX -- [ Pg.880 ]




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Neuroleptics

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