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Antigen recognition interference

I. Interference with antigen recognition. Muromonab CDS is a monoclonal antibody directed against mouse CD-3 that blocks antigen recognition by T-lymphocytes (use in graft rejection). [Pg.300]

Blockade of tissue responses to inflammatory mediators Increased catabolism of IgG antibodies Inhibition of the gene transcription of interleukins Interference with antigen recognition Azathioprine... [Pg.500]

The induction of apoptosis in virus-infected cells is an important defense mechanism of the host. Apoptosis of a virus-infected cell occurs either as a direct response to viral infection or on recognition of infection by the host immune system. Viruses have evolved different strategies to evade host immune responses including inhibition of antibody- and complement-mediated effects, interference with interferons, inhibition and modulation of cytokines and chemokines, blockade of antigen presentation, and also inhibition of apoptosis (Spriggs 1996 Alcami and Koszinowski 2000). [Pg.258]


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See also in sourсe #XX -- [ Pg.304 ]




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