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Antigen-presenting cell maturation

Dendritic cells (DCs) are bone marrow-derived professional antigen-presenting cells (APCs) (1). The function of DCs depends on their maturation stages progenitors in the bone marrow, precursors in the blood, immature DCs in peripheral tissues, antigen-transporting DCs in the afferent lymphatics, and... [Pg.87]

Hacker, H. et al., CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation, Embo J., 17, 6230, 1998. [Pg.78]

Carson MJ, Reilly CR, Sutcliffe JG, Lo D. Mature microglia resemble immature antigen-presenting cells. Glia 1998 22(l) 72-85. [Pg.265]

T-cells T (thymus derived) cell. These white blood cells, known as T lymphocytes, mature in the thymus and have regulatory immune functions. As part of the adaptive (cell-mediated) immune system, these cells can recognize antigens processed by antigen-presenting cells in the context of specific receptors. The cell surface protein CD3 is a marker for these cells. [Pg.789]

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Antigen presentation

Antigen-presenting cells

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