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Antidiabetic drugs thiazolidinediones

ANTIDIABETIC DRUGS OTHER ANTIDIABETIC DRUGS Thiazolidinediones... [Pg.447]

Thiazolidinediones (synonyms glitazones, insulin sensitizers rosiglitazone, pioglitazone) are a novel class of oral antidiabetic drugs that activate the transcription factor peroxisome proliferator-activated receptor (PPARy). Thiazolidinediones ameliorate insulin resistance in obese animal models and in individuals... [Pg.635]

Jordan VC. Antiestrogenic action of raloxifene and tamoxifen today and tomorrow. J. Natl. Cancer Inst. 1998 90 967-971. Day C. Thiazolidinediones a new class of antidiabetic drugs. Diabet. Med. 1999 16 179-192. [Pg.1328]

The oral antidiabetic drugs are the sulfonyiureas, metformin, acarbose, thiazolidinediones, and j repaglinide. [Pg.286]

Sitagliptin is a peptidase-4 (DPP-4) inhibitor that is used as an antidiabetic drug either alone or in combination with metformin or a thiazolidinedione for control of type 2 diabetes mellitus. The synthesis of sitagliptin contains triazole formation followed by coupling with a acid derivative. ... [Pg.389]

Sitagliptin 5 (Januvia, Figure 4.2) is an oral antidiabetic drug of the DPP-4 inhibitor class developed and is marketed by Merck Co. Sitagliptin is used either alone or in combination with other oral antihyperglycemic agents (such as metformin or a thiazolidinedione) for the treatment of type-2 diabetes. [Pg.72]

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See also in sourсe #XX -- [ Pg.32 ]

See also in sourсe #XX -- [ Pg.32 ]



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Antidiabetics

Thiazolidinedione

Thiazolidinedione antidiabetic drugs

Thiazolidinedione antidiabetic drugs

Thiazolidinedione drugs

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