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Antidepressant agents origin

Antidepressive agents which increase synaptic availability of serotonin and noradrenaline have been empirically found to be efficacious against chronic pain, particularly that of neuropathic origin. [Pg.931]

Atomoxetine was originally developed as an antidepressant agent (tomoxetine), but failed to realize this potential. It was abandoned until its use for ADHD was conceived and clinical trials were initiated. During clinical trials its name was changed to atomoxetine to avoid confusion with other medications with similar names (e.g., tamoxifen). It is not currently FDA approved for any indication and is not commercially available anywhere. Materials to support an FDA indication for ADHD were submitted in October, 2001. [Pg.305]

Originally developed as antianginal agent, this drug elicits powerful MAO-inhibitory and antidepressant effects. It appears to be more potent than phenelzine (phenethylhydrazine) in this respect. [Pg.127]


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See also in sourсe #XX -- [ Pg.115 ]




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Antidepressant agents

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