Anticoagulants, oral, skin necrosis

Adrenaline hypertension Anticoagulants, oral skin necrosis Antituberculosis drugs hepatotoxicity Pseudoephedrine toxic epidermal necrolysis SSRIs suicidal behavior Statins acute pancreatitis Ximelagatran liver damage... [Pg.877]

Anthracyclines, 25.533 Antiallergic drugs, ocular treatment, 11.420 Antibacterial drugs, resistance, 31.413, 32.445 intrapartum, 32.446 Anticancer antimetabolites, 29.531 Anticholinergic drugs, 22.507, 31.273 cardiovascular risks, 32.318 Anticoagulants, oral, skin necrosis, 29.358... [Pg.1115]

Coumarin-induced skin necrosis is a rare complication of oral anticoagulant therapy. Especially patients suffering from a rare and life-threatening blood disorder known as protein C deficiency are at risk. In these cases Protein C Concentrate (human). [Pg.372]

Hemorrhagic skin necrosis has been described with all coumarins and indanediones. During the initial phase of oral anticoagulant treatment with these agents, the plasma concentration of protein C falls rapidly in parallel with factor VII. The half-lives of protein C and factor VII... [Pg.986]

Samama M, Horellou MH, Soria J, Conard J, Nicolas G. Successful progressive anticoagulation in a severe protein C deficiency and previous skin necrosis at the initiation of oral anticoagulant treatment. Thromb Haemost 1984 51(l) 132-3. [Pg.995]

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