MAOIs Anticoagulants, oral

Sulfonylureas In acute poisoning with sulfonylureas, the stomach should be washed and treated with activated charcoal, and hypoglycemia must be treated. Sulfonylureas interact with oral contraceptives, thiazide diuretics, corticosteroids, adrenaline, chlorpromazine, ACE inhibitors, some NSAIDs, antihistamines, anticoagulants, MAOIs, antidepressants, and many other drugs. Care must be exercised when treating with sulfonylureas. 

Although some animal data show that the non-selective MAOIs increase the effects of some oral anticoagulants, there appears to be no clinical evidence of an interaction. Moclobemide did not interact with phenprocoumon in a pharmacological study. 

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