Anticancer drug discovery

Yart A, Mayeux P, Raynal P (2003) Gabl, SHP-2 and Other Novel Regulators of Ras Targets for Anticancer Drug Discovery. Curr Cancer Drug Targets 3 177-192... 

Shi LM, Fan Y, Lee JK, Waltham M, Andrews DT, Scherf U, Pauli KD, Weinstein JN. Mining and visualizing large anticancer drug discovery databases. / Chem Inf Comput Sci 2000 40 367-79. 

Neidle S, Parkinson GN (2002) Telomere maintenance as a target for anticancer drug discovery. Nat Rev Drug Discov l(5) 383-393... 

Ma X, Wang Z. (2009) Anticancer drug discovery in the future An evolutionary perspective. Drug Discov Today 14 1136-1142. 

Butler MS, Newman DJ. (2008) Mother nature s gifts to diseases of man The impact of natural products on anti-infective, anticholestemics and anticancer drug discovery. Prog Drug Res 65 3 44. 

Hoffman, R. M. (1999) Orthotopic metastatic mouse models for anticancer drug discovery and evaluation a bridge to the clinic. Invest New Drugs 17, 343-359. 

LM Shi, Y Fan, TG Myers, PM O Connor, KD Pauli, SH Friend, JN Weinstein. Mining the NCI anticancer drug discovery databases genetic function approximation for the QSAR study of anticancer ellipticine analogues. J Chem Inf Comput Sci 38 189-199, 1998. 

Boyd MR, Pauli KD. Some practical considerations and applications of the national cancer institute in vitro anticancer drug discovery screen. Drug Dev Res 1995 34 91-109. 

Boyd MR. The NCI in vitro anticancer drug discovery screen Concept, implementation, and operation, 1985-1995. In Teicher BA, editor. Anticancer drug development guide Preclinical screening, clinical trials and approval. Totowa, NJ Humana Press 1997. p. 23-42. 

Shi LM, Myers TG, Fan Y et al. Mining the National Cancer Institute Anticancer Drug Discovery Database Cluster analysis of ellipticine analogs with p53-inverse and central nervous system-selective patterns of activity. Mol Pharmacol 1998 53 241-51. 

Buolamwini JK. Novel anticancer drug discovery. Curr Opin Chem Biol. 1999 3(4) 500-509. 

An essential step in an efficient natural product drug discovery program is the judicious selection of an initial screening strategy. The in vitro methods available for anticancer drug discovery can be grouped into two major categories. These are the... 

Jain, K. K., 2002b, Proteomics-based anticancer drug discovery and development. Techn... 

Mans DRA, Jung FA, Schwartsmann G. Anticancer drug discovery and development. J Brazilian Assoc Advancement Sci 1994 46 70-81. 

Petak, I., Schwab, R., Orfi, L., Kop>per, L., and Keri, G. 2010. Integrating molecular diagnostics into anticancer drug discovery. Nat. Rev. Drug Discov. 9(7) 523-35. 

---