Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Anticancer complexes

Mackay, F. S. Photoactive platinum azide anticancer complexes, PhD Thesis, University of Edinburgh, Edinburgh, 2006. [Pg.59]

Fig. 7. X-ray crystal structure of the sterically hindered 2-picoline anticancer complex 9 in comparison with its 3-picoline analog. The 2-methyl group in 9 lies directly over the Pt-square plane (H3C Pt 3.22 A). The hydrogen atoms are omitted. Adapted from 44). Fig. 7. X-ray crystal structure of the sterically hindered 2-picoline anticancer complex 9 in comparison with its 3-picoline analog. The 2-methyl group in 9 lies directly over the Pt-square plane (H3C Pt 3.22 A). The hydrogen atoms are omitted. Adapted from 44).
Fig. 8. X-ray crystal structure of the raras-Pt(II)-iminoether anticancer complex 18. Adapted from (129). [Pg.205]

Chart 4 Interactions within guanine (G) and adenine (A) adducts of arene Ru-en anticancer complexes... [Pg.33]

In order to target drug delivery, it is very important to study the distribution of the drug within the body. For example radiolabelling of the anticancer complex [Ru (r 6-fhiorene)Cl(en)]PF6 with the (3-emitter 106Ru (half-life = 1.01 y) has allowed its biodistribution to be studied 0.25 h post i.v. injection at a dose of 25 mg kg-1, 106Ru is well distributed throughout the tissues of a rat [155]. [Pg.44]

Melchart M, Sadler PJ (2006) Ruthenium arene anticancer complexes. In Jaouen G (ed) Bioorganometallics. Wiley-VCH, Weinheim, pp 39-64... [Pg.50]

Yan YK, Melchart M, Habtemariam A, Sadler PJ (2005) Organometallic chemistry, biology and medicine ruthenium arene anticancer complexes. Chem Commun 4764-4776... [Pg.50]

Wang F, Chen H, Parsons S, Oswald IDH, Davidson JE, Sadler PJ (2003) Kinetics of aquation and anation of mthenium(II) arene anticancer complexes, acidity and X-ray structures of aqua adducts. Chem Eur J 9 5810-5820... [Pg.51]

Wang F, Bella J, Parkinson JA, Sadler PJ (2005) Competitive reactions of a ruthenium arene anticancer complex with histidine, cytochrome c and an oligonucleotide. J Biol Inorg Chem 10 147-155... [Pg.52]

Liu LH-K, Wang F, Parkinson JA, Bella J, Sadler PJ (2006) Ruthenation of duplex and single-stranded d(CGGCCG) by organometallic anticancer complexes. Chem Eur J 12 6151-6165... [Pg.52]

Pizarro AM, Sadler PJ (2009) Unusual DNA binding modes for metal anticancer complexes. Biochimie 91 1198-1211... [Pg.52]

Wang F, Xu J, Habtemariam A, Bella J, Sadler PJ (2005) Competition between glutathione and guanine for a ruthenium(II) arene anticancer complex detection of a sulfenato intermediate. J Am Chem Soc 127 17734—17743... [Pg.52]

Wang F, Weidt S, Xu J, Mackay CL, Langridge-Smith PRR, Sadler PJ (2008) Identification of clusters from reactions of ruthenium arene anticancer complex with glutathione using nanoscale liquid chromatography fourier transform ion cyclotron mass spectrometry combined with 180-labeling. J Am Soc Mass Spectrom 19 544-549... [Pg.52]

Hu W, Luo Q, Ma X, Wu K, Liu J, Chen Y, Xiong S, Wang J, Sadler PJ, Wang F (2009) Arene control over thiolate to sulfinate oxidation in albumin by organometallic ruthenium anticancer complexes. Chem Eur J 15 6586-6594... [Pg.52]

Sriskandakumar T, Petzold H, Bruijnincx PCA, Habtemariam A, Sadler PJ, Kennepohl P (2009) Influence of oxygenation on the reactivity of ruthenium-thiolato bonds in arene anticancer complexes insights from XAS and DFT. J Am Chem Soc 131 13355-13361... [Pg.53]

Bugarcic T, Habtemariam A, Deeth RJ, Fabbiani FPA, Parsons S, Sadler PJ (2009) Ruthe-niumfll) arene anticancer complexes with redox-active diamine ligands. Inorg Chem 48 9444-9453... [Pg.53]

Dougan SJ, Habtemariam A, McHale SE, Parsons S, Sadler PJ (2008) Catalytic organometallic anticancer complexes. Proc Natl Acad Sci USA 105 11628-11633... [Pg.54]

Zobi F, Mood BB, Wood PA, Fabbiani FPA, Parsons S, Sadler PJ (2007) Tagging (arene) ruthenium(II) anticancer complexes with fluorescent labels. Eur J Inorg Chem 2783-2796... [Pg.55]

See other pages where Anticancer complexes is mentioned: [Pg.427]    [Pg.6]    [Pg.8]    [Pg.8]    [Pg.16]    [Pg.23]    [Pg.33]    [Pg.40]    [Pg.46]    [Pg.187]    [Pg.23]    [Pg.25]    [Pg.27]    [Pg.29]    [Pg.31]    [Pg.33]    [Pg.35]    [Pg.37]    [Pg.39]    [Pg.39]    [Pg.41]    [Pg.43]    [Pg.45]    [Pg.47]    [Pg.49]    [Pg.50]    [Pg.51]    [Pg.52]    [Pg.53]    [Pg.55]   
See also in sourсe #XX -- [ Pg.231 ]



SEARCH



© 2024 chempedia.info