Anticancer agents dictyostatin

Paterson, 1., Gardner, N.M., Poullennec, K,G and Wright, A.E. (2008a) Synthesis and biological evaluation of 10,11-dihydrodictyostatin, a potent analogue of the marine anticancer agent dictyostatin. J. Nat. Prod., 71, 364-369. 

Dictyostatin [90a] Due to its exceptional biological profile as a promising anticancer agent at nanomolar concentrations, tremendous efforts have been devoted to the synthesis of dictyostatin (131). Indeed, this natural product that was extracted from a sponge from the Indian Ocean by Pettit et al. 

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