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Antibody melanocyte-specific

Figure 7.3 The ER 1D5 peptide only binds to the ER 1D5 mAb (upper left and lower right). Other mAbs do not bind. The antibody abbreviations in the lower panel are Her2 11G5, and 9C2, human epidermal growth factor receptor type 2 clones 11G5 and 9C2 Mela-HMB45, melanocyte-specific antibody clone HMB45 Vimen V9, vimentin clone V9 Anti-LCA, anti-leukocyte common antigen clones PD7/26 and 2B11, combined as a cocktail Mouse poly IgG, mouse polyclonal IgG. Reproduced with permission from Sompuram et al.7... Figure 7.3 The ER 1D5 peptide only binds to the ER 1D5 mAb (upper left and lower right). Other mAbs do not bind. The antibody abbreviations in the lower panel are Her2 11G5, and 9C2, human epidermal growth factor receptor type 2 clones 11G5 and 9C2 Mela-HMB45, melanocyte-specific antibody clone HMB45 Vimen V9, vimentin clone V9 Anti-LCA, anti-leukocyte common antigen clones PD7/26 and 2B11, combined as a cocktail Mouse poly IgG, mouse polyclonal IgG. Reproduced with permission from Sompuram et al.7...
Gown, A. M., Vogel, A. M, Hoak, D., Gough, F., and McNutt, M. A. (1986) Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes. Am J Pathol 123,195-203... [Pg.426]

Because muscle-specific actin (recognized by monoclonal antibody HHF-35), alpha-isoform ( smooth muscle ) actin (recognized by antibody 1A4), and caldesmon are also preferentially seen in nonepithelial, nonmelanocytic, nonglial tissues, those determinants would be unexpected in melanocytic neoplasms. Indeed,... [Pg.190]

Trefzer U, Rietz N, Chen Y, et al. SM5-1 a new monoclonal antibody which is highly sensitive and specific for melanocytic lesions. Arch Dermatol Res. 2000 292 583-589. [Pg.201]

Adema GJ, deBoer AJ, VantHullenaar R, et al. Melanocyte lineage-specific antigens recognized by monoclonal antibodies NKI-beteb, HMB-50, and HMB-45 are encoded by a single cDNA. Am J Pathol. 1993 143 1579-1585. [Pg.201]

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Melanocytes

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