Antibacterial drugs commonly called

Antibacterial agents may be classified according to the class of target microorganism. Accordingly, antibacterial agents that inhibit only bacteria are described as narrower medium-spectrum, whereas those that also inhibit mycoplasma, rickettsia, and chlamydia (so-called atypical bacteria) are described as broad-spectrum. The spectrum of activity of common antibacterial drugs is shown in Table 1.1. 

Various mass spectral techniques have been used in characterizing various metal-containing macromolecules. The focus will be on two techniques. The first one is the most commonly employed mass spectrophotometer setup, called high-resolution electron impact mass spectrometry (HREl-MS). The second system is the matrix-assisted laser desorption ionization (MALDl) system. Illustrative examples of these two procedures are given for the products of Group IVB metallocene dichlorides and the antibacterial drug norfloxacin, scheme 8. 

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