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Antiarrythmic agents

It will be recalled that certain local anesthetic amides, such as procainamide and lidocaine, are active antiarrythmic agents. Annelation of a second aromatic ring is consistent with bioactivity. Bunaftine (21) is such an agent, prepared simply from reaction of the acid chloride of 1-naphthoic acid and... [Pg.211]

Interestingly, when propranolol is quaternized with methyl chloride, it loses its p-blocker activity and becomes the antiarrythmic agent pranolium chloride (22).8... [Pg.212]

Sotalol (-)-Sotalol (3-adrenoceptor biocker (-l-)-Sotaioi antiarrythmic agent Drayer ... [Pg.539]

The content of quinidine is low in all species, about 10% of the total content. Since quinidine is frequently used as an antiarrythmic agent, quinine is transformed industrially to quinidine by oxidation and reduction, to quinidine. [Pg.118]

Disopyramide, an antiarrythmic agent, and its mono-N-dealkylated metabolite present in the extracts derived from plasma and urine Ion-pair chromatography ODS-silica Methanol/water (53 47) containing heptanesulphonic acid... [Pg.225]

Reseai ch aimed at the identification of novel antiarrythmic agents is targeting Cl channels. Cl channels are involved in cardiac arrythmia, asthma, CF and diarrhea, thus representing targets for therapeutic approaches. [Pg.167]

Give a comprehensive account of antiarrythmic agents used as cardiovascular drugs. Support your answer with at least one example from each category. [Pg.371]

See other pages where Antiarrythmic agents is mentioned: [Pg.208]    [Pg.714]    [Pg.385]    [Pg.4]    [Pg.140]    [Pg.244]    [Pg.120]    [Pg.33]    [Pg.244]    [Pg.366]    [Pg.374]    [Pg.318]   
See also in sourсe #XX -- [ Pg.179 ]



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Antiarrythmic

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