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Antianxiety drugs buspirone

Jajoo, H.K., Mayol, R.R, Labudde, J.A., and Blair, LA. (1989) Metabolism of the antianxiety drug buspirone in human subjects. Drug Metab Dispos 17 634-640. [Pg.351]

More importantly, buspirone has a much better side-effect profile than traditional antianxiety drugs. Buspirone seems to produce less sedation and psychomotor impairment than benzodiazepine agents.2... [Pg.71]

HK Jajoo, LA Blair, LJ Klunk, RF Mayol. In vitro metabolism of the antianxiety drug buspirone as a predictor of its metabolism in vivo. Xenobiotica 20 779, 1990. [Pg.196]

FIGURE 16.1 (A) Antianxiety drug buspirone 1. (B) Enzymatic resolution of 6-acetoxy-... [Pg.217]

Some antianxiety drug, such as buspirone (BuSpar), seem to have less abuse potential and less effect on motor ability and cognition than that of Hie other anfianxiety drug. [Pg.276]

Buspirone causes less additive CNS depression than do the other antianxiety drugs. However, it is recommended that concurrent use with a CNS depressant be avoided. Buspirone may increase serum digoxin levels, which increases the risk of digitalis toxicity. [Pg.277]

In summary, buspirone is an effective generalized anxiety treatment that differs from conventional antianxiety drugs in speed of symptom reduction and types of symptoms affected. Although buspirone might seem to be the drug of choice for treatment of chronic anxiety, it has not displaced the use of benzodiazepines in the treatment of anxiety, perhaps because of its side-effect profile [dizziness, sedation, nausea], slow onset of action, and the opinion of some clinicians that its anxiolytic efficacy is less robust than that of benzodiazepines. Buspirone is accepted as an anxiolytic treatment much more widely in the United States than in most other countries [Kunovac and Stahl 1995]. [Pg.361]

The atypical antianxiety medication buspirone has been used with some success with GAD patients. This medication offers the benefits of reduced rumination and worry, but without the problems of sedation and potential drug dependence seen with benzodiazepines. Buspirone is not addictive and thus provides a treatment option for GAD patients with substance abuse risk. [Pg.93]

BuSpar (buspirone) An antianxiety drug that is not often associated with abuse because of the absence of withdrawal phenomena, cognitive impairment, and sedation. It has a short half-life and therefore must be taken several times daily. It is also said not to have the same addicting or euphoric quality that is often noted in the benzodiazepines. BuSpar is not a benzodiazepine and is referred to as a nonbenzodiazepine. BuSpar is generally prescribed for a limited time to help control the symptoms of anxiety and allows the client to be calmer while learning new ways of coping with anxiety-producing events. [Pg.298]

We think that buspirone may be the drug of choice for many patients with GAD who have not taken BZDs previously. Buspirone may also have an advantage in patients who have problems with BZD withdrawal symptoms. Increased antianxiety effects have been observed in some patients treated concurrently with low doses of buspirone and a BZD (Table 12-4). Further, buspirone may be indicated in individuals with GAD with histories of chemical dependency who have failed or who could not tolerate antidepressants ( 54). [Pg.233]

Other drugs of the depressant, antianxiety, antipyschotic, and anticonvulsive types are being investigated as treatments for cocaine abuse. Those which have been or will be covered in this course include the heterocyclic antidepressants desipramine and imipramine, which diminish cocaine use and craving as well as improve the outcome in the first few months of treatment. Buprenorphine (depressant) may augment the reward system (it has been found to suppress self-administration of cocaine in monkeys). Lithium sometimes works for those who are clinically depressives. Carbamazapine, bromocriptine and mazindol are also used as well as fluphenthixol and buspirone. [Pg.159]


See other pages where Antianxiety drugs buspirone is mentioned: [Pg.349]    [Pg.96]    [Pg.349]    [Pg.96]    [Pg.274]    [Pg.359]    [Pg.326]    [Pg.392]    [Pg.483]    [Pg.626]    [Pg.194]    [Pg.361]    [Pg.92]    [Pg.274]    [Pg.415]    [Pg.242]    [Pg.443]    [Pg.95]    [Pg.71]    [Pg.71]    [Pg.72]    [Pg.588]    [Pg.103]    [Pg.274]    [Pg.594]    [Pg.601]   
See also in sourсe #XX -- [ Pg.71 , Pg.72 ]




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