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Anti-malarial Endoperoxides

Artemisinin ( qinghaosu ) (18), a sesquiterpene lactone antimalarial compound with an endoperoxide group, discovered in the Peoples Republic of China as a constituent of Artemisia annua L., has created great interest in the biomedical community, owing to its unique mechanism of action on the heme complex. Artemisinin serves as an option for the treatment of chloroquine (4l)-resistant malaria and is used in some Asian countries as an antimalarial. However, the use of artemisinin as a single agent anti-malarial is a potential risk since the malaria parasite may become resistant to this compound class. [Pg.16]

VII. ANTI MALARIAL ACTIVITIES OF SYNTHETIC ENDOPEROXIDE ANTIMALARIALS... [Pg.1332]

See other pages where Anti-malarial Endoperoxides is mentioned: [Pg.1311]    [Pg.19]    [Pg.1311]    [Pg.19]    [Pg.190]    [Pg.1283]    [Pg.190]    [Pg.1283]    [Pg.358]    [Pg.167]    [Pg.289]   


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Anti-malarial

Anti-malarials

Endoperoxidation

Endoperoxide

Endoperoxides/endoperoxidation

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