Anorexia nervosa antipsychotics

Three main classes of drugs have been considered in the treatment of anorexia nervosa antipsychotics, antidepressants and antihistamines. 

Antipsychotics also have been used in the treatment of anorexia nervosa. The apparent role of dopamine in feeding and satiety involves increased receptor activity, producing symptoms similar to those found in anorexia nervosa. Thus, it seems reasonable to use dopamine antagonists to alter these behaviors. It also seems appropriate to use the sedative side effects of these drugs to decrease anxiety associated with eating. 

In conclusion, while the core symptoms of anorexia nervosa appear to be largely refractory to psychotropic drugs, it would appear, on the basis of the limited trial data, that the newer antipsychotic compounds, such as olanzapine and amisulpiride, show promise. Antidepressant drugs can help to reduce the relapse rate after successful treatment (Casper 2002). 

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