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Annona densicoma

Structural work and chemistry is reported for active compounds from Annona densicoma, Cudrania cochinchinensi s, Desfontainia spinosa Pararistolochia flos-aviSy Podocarpus species, Psorospermum febrifuguniy and Spathelia sorbifolia. A number of these novel compounds exhibit sufficient activity to initiate studies of their mechanism of action and analog synthesis. [Pg.291]

In preliminary screening, extracts of Annona densicoma Mart. (Annonaceae) collected in Peru (South America) were active in the 9ASK and 9PS cell culture systems. Activity-directed fractionation of an ethanolic stem-bark extract resulted in the isolation of a highly cytotoxic compound named annonacin (1, ref. 50). [Pg.295]

Information on stereochem. currently fragmentary (1995). Four stereoisomers, cis- and rr 5-Isoannonacins and cis- and /r 7 5-Annonacin-A-ones apparently isol. Constit. of Annona densicoma and Asimina triloba. 10-Ketone [123266-23-9]. Isoannonacin-lO-one M 594.871... [Pg.242]

See other pages where Annona densicoma is mentioned: [Pg.572]    [Pg.38]    [Pg.295]    [Pg.242]    [Pg.572]    [Pg.38]    [Pg.295]    [Pg.242]   
See also in sourсe #XX -- [ Pg.9 , Pg.395 ]

See also in sourсe #XX -- [ Pg.291 , Pg.295 ]



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Annona

Annona densicoma annonacin from

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