Animal imaging

Hao L, Zhang H, Tang Z et al (2008) Micro-computed tomography for small animal imaging technological details. Prog Nat Sci 18(5) 513-521... 

Cell and Small Animal Imaging with Surface-Enhanced Raman Spectroscopic (SERS) and Other Nanoparticle Tags... 

Bushberg JT, Seibert JA, Leidholdt Sr EM, Boone JM (2002). The essential physics of medical imaging, 2nd ed. Lippincott, Williams and Wilkins, Philadelphia Chatziioannou AF, Cherry SR, Shao Y et al (1999). Performance evaluation of microPET a high-resolution lutetium oxyorthosilicate PET scanner for animal imaging. J Nucl Med 40 1164... 

In addition to the integration of different modalities into one system, a common table can be used to exchange the patient or animal rapidly and reproducibly. This approach can additionally be supported by a position tracking tool, which has already been used for animal imaging without the use of anesthetics [24]. Based on the concept of exchangeable tables, new scanner combinations are expected to become available in the near future. 

Kodak ImageStation 2000MM CCD camera with selectable multi-wavelength illumination source for imaging microtiter plates can also be used for radiography and whole animal imaging. www.kodak.com... 

Iwata K, MacDonald L R, Hwang A B, et al. (2002). CT-SPECT for small animal imaging with A-SPECT. J. Nucl. Med. 43(suppl.) 10P-Abst. No. 35. 

Lewis J S, Achilefu S, Garbow J R, et al. (2002). Small animal imaging Current technology and perspectives for oncological imaging. Eur. J. Cancer. 38 2173-2188. 

Certainly in human patients the condition of a well-localised inclusion in a homogeneous, nonfluorescent bulk medium is not fulfilled. The condition is better, yet not perfectly, met in small animals where the tissue depth does not exceed a few millimeters. The contribution of the bulk medium and its inhomogeneity is correspondingly smaller. Therefore DOT fluorescence is currently used mainly for small-animal imaging (see section below). 

The common use of fluorescence in small-animal imaging makes time-resolution almost mandatory. As for the other DOT applications, time-resolved small-animal imaging is performed by modulation techniques and by TCSPC. TCSPC has the benefit that it is able to resolve complex decay functions. The principle of a typical time-resolved instrument [174] is shown in Fig. 5.57. 

Jiang, W., Papaji-, et al. Semiconductor quantum dots as contrast agents for whole animal imaging. Trends in Biotechnology,22( 12), 607-609 (2004). 

Ma, R., et al. Multispectral optoacoustic tomography (MSOT) scanner for whole-body small animal imaging. Optics Express 17(24), 21414-21426 (2009)... 

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