Anglo Scandinavian Cardiac Outcomes Trial Lipid-Lowering Arm

I 5 Sever PS, Dahlof B, Poulter NR, et al, Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA) a multicentre randomised controlled trial, Lancet 2003 361 1 149-1 158. 

The diabetes subgroup (n = 2532) from the Anglo Scandinavian Cardiac Outcomes Trial Lipid-Lowering Arm (ASCOT-LLA) showed a similar trend (test for heterogeneity not significant) to reduction of CVD events as those without diabetes. This nial is of particular interest because the benefits of statin therapy (atorvastatin 10 mg/day) were seen in well-ffeated hypertensive patients [51]. 

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