Angiotensin converting enzyme pregnancy

Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor and ACE inhibitors should be avoided during pregnancy. ACE inhibitors may adversely affect fetal and neonatal blood pressure control and renal function. They may also cause neonatal skull defects. 

Shotan A, Widerhom J, Hurst A, EUcayam U. Risks of angiotensin-converting enzyme inhibition during pregnancy experimental and clinical evidence, potential mechanisms, and recommendations for use. Am J Med 1994 96 451 56. 

BuUo M, Tschumi S, Bucher BS, Bianchetti MG, Simonetti GD. Pregnancy outcome following exposure to angiotensin-converting enzyme inhibitors or angiotensin receptor antagonists a systematic review. Hypertension 2012 60 444-50. 

Evaluation or re-evaluation of family history and of pregnancy may reveal previous cases of fetal or neonatal death suggestive of inherited disorders or syndromes. Administration of angiotensin-converting enzyme inhibitors (ACE-inhibitors) for hyperten-... 

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