Angiotensin converting enzyme gene

Schunkert H. Polymorphism of the angiotensin-converting enzyme gene and cardiovascular disease. J Mol Med 1997 75 867-875. 

Buikema H, Pinto YM, Rooks G, Grandjean JG, Schunkert H, van Gilst WH. The deletion polymorphism of the angiotensin-converting enzyme gene is related to phenotypic differences... 

Prasad A, Narayanan S, Waclawiw MA, Epstein N, Quyyumi AA. The insertion/deletion polymorphism of the angiotensin-converting enzyme gene determines coronary vascular tone and nitric oxide activity. J Am Coll Cardiol 2000 36 1579-1586. 

Butler R, Morris AD, Burchell B, Struthers AD. DD angiotensin-converting enzyme gene polymorphism is associated with endothelial dysfunction in normal humans. Hypertension 1999 33 1164-1168. 

Perticone F, Ceravolo R, Maio R, Ventura G, Zingone A, Perrotti N, Mat-tioli PL. Angiotensin-converting enzyme gene polymorphism is associated with endothelium-dependent vasodilation in never treated hypertensive patients. Hypertension 1998 31 900-905. 

Tian B, Meng QC, Chen Y-F, Krege JH, Smithies O, Oparil S. Blood pressures and cardiovascular homeostasis in mice having reduced or absent angiotensin-converting enzyme gene function. Hypertension 1997 30[part I] 128—133. 

Yang, J.D., Feng, G., Zhang, J., et al. (2000) Association between angiotensin-converting enzyme gene and late onset Alzheimer s disease in Han Chinese. Neurosci. Lett., 295, 41 4. 

Cheng, C.Y., Hong, C.J., Liu, H.C., Liu, T.Y., Tsai, S.J. (2002) Study of the association between Alzheimer s disease and angiotensin-converting enzyme gene polymorphism using DNA from lymphocytes. Eur. Neurol., 47, 26-29. 

Purandare, N., Oude Voshaar, R.C., Davidson, Y., et al. (2006) Deletion/insertion polymorphism of the angiotensin-converting enzyme gene and white matter hyperintensities in dementia a pilot study. J. Am. Geriatr. Soc., 54, 1395-1400. 

L2. Lee, D. Y., Kim, W., and Kang, S. K., Angiotensin-converting enzyme gene polymorphism in patients with minimal-change nephrotic syndrome and focal segmental glomerulosclerosis. Nephron 77,471-473 (1997). 

The mechanism of fenfluramine-associated pulmonary hypertension has been reviewed (SEDA-21, 3). Since only a minority of patients exposed to fenfluramines develop pulmonary hypertension, it has been postulated that a subset may be genetically susceptible. Whether there is a related genetic abnormality in the familial PPH gene located on chromosome 2q (67) or an abnormality of the angiotensin-converting enzyme gene (68) has yet to be explored. 

O Toole L, Stewart M, Padfield P et al (1998) Effect of the insertion/deletion polymorphism of the angiotensin-converting enzyme gene on response to angiotensin-converting enzyme inhibitors in patients with heart failure. J Cardiovasc Pharmacol 32 988-994... 

Stavroulakis GA, Makris TK, Krespi PG, et al. Predicting response to chronic antihypertensive treatment with fosinopril The role of angiotensin-converting enzyme gene polymorphism. Cardiovasc Drugs Ther 2000 14 427-432. 

Kohno M, Yokokawa K, Minami M, et al. Association between angiotensin-converting enzyme gene polymorphisms and regression of left ventricular hypertrophy in patients treated with angiotensinconverting enzyme inhibitors. Am J Med 1999 106 544-549. 

Jacobsen P, Rossing K, Rossing P, et al. Angiotensin-converting enzyme gene polymorphism and ACE inhibition in diabetic nephropathy. Kidney Int 1998 53 1002-1006. 

Evans, A. E., et al., Polymorphisms of the angiotensin-converting-enzyme gene in subjects who die from coronary heart disease. QJ Med, 1994. 87(4) p. 211-4. 

Schunkert, H., et al., Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy [see comments]. N Engl J Med, 1994. 330(23) p. 1634-8. 

Montgomery, H., et al., Angiotensin-converting-enzyme gene insertion/deletion polymorphism and response to physical training [see comments]. Lancet, 1999. 353(9152) p. 541-... 

Arbustini E, Grasso M, Leo G, et al. Polymorphism of angiotensin-converting enzyme gene in sarcoidosis. Am J Respir Crit Care Med 1996 153(2) 851-854. 

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