Androgens metabolism

Male mouse urine applied directly to the external nares of the female produces pregnancy block (Dominic, 1964). In mice, the vomeronasal mediates this block (Bellringer etal., 1980). The pregnancy-block pheromone of the male may be a product of androgen metabolism, and not one of androgen-dependent... 

SR046 Sultan, C., A. Terraza, C. Devillier, et al. Inhibition of androgen metabolism and binding by a liposterolic extract of Serenoa repens B in human foreskin fibroblasts. J Steroid Biochem 1984 ... 

We studied by GC-MS the urinary excretion of a single patient with a documented mutation [49] and have found that the 5/3-reduced androgen metabolite excretion relative to 5a is decreased by about 80%, and 5/ -corticosteroid metabolite excretion is essentially absent [63]. To date there has no report of an adverse endocrine phenotype related to corticosteroid, mineralocorticoid, or androgen metabolism. 

Ross RK, Pike MC, Coetzee GA, Reichardt JK, Yu MC, Feigelson H, Stanczyk FZ, Kolonel LN, Henderson BE (1998) Androgen metabolism and prostate cancer establishing a model of genetic susceptibility. Cancer Res 58 4497 -504... 

Sooriyamoorthy M, Gower DB, Eley BM. Androgen metabolism in gingival hyperplasia induced by nifedipine and cyclosporin. J Periodontal Res 1990 25(l) 25-30. 

Levin W, Welch RM, Conney AH. 1974. Increased liver microsomal androgen metabolism by phenobarbital correlation with decreased androgen action on the seminal vesicles of the rat. J. Pharmacol. Exp. Ther. 188 287-92... 

D6. Dell Acqua, S., Mancuso, S., Benagiano, G., Wiquist, N., and Diczfalusy, E., Androgen metabolism in the human foeto-placental imit at mid-term. Excerpta Med. Intern. Congr. Ser. Ill, 60 (1966). 

Garrett WM, Hoover DJ, Shackleton CH, Anderson LD (1991) Androgen metabolism by porcine granulosa cells during the process of luteinization... 

One of the end products of androgen metabolism. It is excreted in the urine and can be measured as part of the 17-oxosteroid group of compounds. 

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