Analyzers computer-based clinical

These detection schemes are necessarily invasive. Non-invasive methods have been developed based on measuring the spatial distribution of light, diffusely reflected from the tissue surface, as illustrated in Figure 15. This can be analyzed to determine jj, and and thereby to calculate the light distributions e.g. the fluence-depth/radius curve using Equations (3) and (4) or (5) and (4), or computational models for any given source configuration. Specialized diffuse reflectance probes have been developed, both for accessible body surfaces and for endoscopic application. At present these techniques are not in common use for clinical PDT. 

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