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Analysis of Diverse Libraries

0 Rang (Tanimoto Coaft.) 1 0 Range (Tanimoto Coetf.) 1 0 Range (Tanimoto Coed.) 1 [Pg.433]

20 Diversity Matrix using Arpttrery Descriptors 0 Range (Tanimoto Coaff.) 1  [Pg.433]

2D Diversity Matrix using Arbitrary DMcriptors 0 Range (Tanimoto Coefl.) 1  [Pg.433]

The rational design of combinatorial libraries and assessment of compound databases is an important issue to optimize resources in today s discovery strategies. There is a growing interest in augmenting the structural and biological diversity in databases, and how to relate chemical with biological diversity. Many approaches have been reported towards the design of combinatorial libraries, molecular diversity considerations, and vali- [Pg.433]


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