Calcium-channel blockers Anaesthetics, local

ANAESTHETICS - LOCAL CALCIUM CHANNEL BLOCKERS Case reports of severe 1 BP when a bupivacaine epidural was administered to patients on calcium channel blockers Additive hypotensive effect both bupivacaine and calcium channel blockers are cardiodepressant. In addition, epidural anaesthesia causes sympathetic block in the lower limbs, which leads to vasodilatation and 1 BP Monitor BP closely. Preload intravenous fluids prior to the epidural... 

Feldene piroxicam. felodipine [ban, inn, usan] (Plendil etc.) is a dihydropyridine calcium-channel blocker with VASODILATOR properties, which can be used in ANTIHYPERTENSIVE therapy and antianginal prophylaxis, felypressin [ban, inn, usan] ([Phe Lys ]vasopressin phelypressin PLV2 Octapressin Octopressin ) is a synthetic analogue of vasopressin. It is a VASOCONSTRICTOR and is incorporated into LOCAL ANAESTHETIC preparations to prolong their duration of action. (It is a constituent with prilocaine of Citanest with Octapressin .)... 

This section is mainly concerned with the class I antiarrhythmics, which also possess some local anaesthetic properties, and with class IH antiarrhythmics. Antiarrhythmics that fall into other classes are dealt with under beta blockers , (p.833), digitalis glycosides , (p.903), and calcium-channel blockers , (p.860). Some antiarrhythmics that do not fit into the Vaughan Williams classification (see Table 9.1 , (below)) are also included in this section (e.g. adenosine). Interactions in which the an-tiarrhythmic drug is the affecting substance, rather than the drug whose activity is altered, are dealt with elsewhere. 

---