An Absolute Asymmetric Synthesis with Quantitative Enantiomeric Yield

An Absolute Asymmetric Synthesis with Quantitative Enantiomeric Yield.—The 

It is conceivable that in such an arrangement unfavourable diastereomeric interactions can arise at the R)- S) contacts which account for the metastability of the completely disordered phase. We tried then to reduce the number of unwanted (/ )-(5) contacts by intercalating molecules of (2) with, for example, the isopropyl homo- 

Kitaigorodskii in Molecular Crystals and Molecules , Academic, New York, 1973. 

In spite of the differences in space groups, there is a clear correlation between the two structures the two axes, of lengths 7 and 5 A, are almost identical, while the third axis is doubled, doubling thus the number of molecules in the unit cell. Since the 7 A axis is the polymerization axis, it follows that the stack of translationally related molecules is left unchanged, while the weak van der Waals interstack contacts are slightly modified. 

We have thus demonstrated that a system can be planned from the beginning in such a way that it is suited, from both chemical and crystallographic points of view, to a predetermined aim of asymmetric synthesis, making use only of the existing 

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Addadi, L., Vanmil, J., Lahav, M., Photo polymerization in Chiral Crystals. 4. Engineering of Chiral Crystals for Asymmetric [2ji + 2n] Photo polymerization Execution of an Absolute Asymmetric Synthesis with Quantitative Enantiomeric Yield, J. Am. Chem. Soc. 1982, 104, 3422 3429. 

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