Magnesium hydroxide Amoxicillin

Deppermann K-M, Lode H, HofQ en G, Tschink G, Kalz C, Koeppe P. Influence of ranitidine, pirenzepine, and aluminum magnesium hydroxide on the bioavailability of various antibiotics, including amoxicillin, cephalexin, doxycycline and amoxicillin-clavulanic acid. Antmdcrob Agents Chemodier( 9Z9) 33,1901-1907. 

The pharmacokinetics of amoxicillin 1 g, and both amoxicillin and clavulanic acid (given as co-amoxiclav 625 mg), were not significantly altered by 10 doses of aluminium/magnesium hydroxide (Maalox) 10 mL, with the last dose given 30 minutes before amoxicillin. Another study found that four 40-mg doses of aluminium hydroxide (Aludrox) given at 20 minute intervals had no effect on the pharmacokinetics of either amoxicillin or clavulanic acid (given as co-amoxiclav 750 mg with the second dose of antacid). ... 

The absorption of raloxifene is reduced by colestyramine, and their concurrent use is not recommended. No clinically relevant changes in raloxifene pharmacokinetics occur with alumini-um/magnesium hydroxide, amoxicillin, ampicillin or calcium carbonate. Raloxifene does not alter digoxin or methylprednisolone levels. Oral antibacterials, antihistamines, aspirin, benzodiazepines, H2-receptor antagonists, ibuprofen or paracetamol (acetaminophen) were used in clinical studies without any obvious effect on raloxifene levels. Smoking does not appear to alter the efficacy of raloxifene. 

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