Aminoisobutyric aciduria

Bacterial contamination of the urine may result in strongly increased levels of uracil due to the bacterial degradation of pseudouridine. Thymine-uraciluria, which is indicative of a dihydropyrimidine dehydrogenase or dihydropyrimidinase deficiency, may also result from increased tissue degradation. However, the latter situation is also characterized by hyper-/l-aminoisobutyric aciduria and hyper-/f-alaninuria [6]. Under alkaline conditions, due to the presence of bacterial contamination, the de-oxynucleosides may be hydrolyzed toward their corresponding nucleoside bases. 

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