Aminofumaric acid diamide

Oxalacetate and Related Compounds. Mitchell and Houlahan have suggested several plausible intermediates that may be involved in pyrimidine biosynthesis in Neurospora. Oxalacetic acid, aminofumaric acid, and aminofumaric acid diamide (Fig. 10) stimulated the growth of mutants with partial blocks in pyrimidine synthesis. Lagerkvist et al. compared the incorporation of N -labeled aspartic acid and (8,7-carbon-labeled aspartate into the pyrimidines of regenerating rat liver. Since nitrogen-labeled aspartate was less effective than carbon-labeled aspartate as a pyrimidine precursor, the authors concluded that aspartic acid was... 

Ureidofumaric acid Orotic add (or ribose derivative) Aminofumaric add diamide... 

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