1 -aminocyclopropane-1 -carboxylic

Aminocyclopropane-1-Carboxylate Synthase, an Enzyme of Ethylene Biosynthesis... 

Scheme 1 The ethylene biosynthetic pathway. The enzymes catalyzing each step are shown above the arrows. SAM S-adenosyl-L-methionine SAMS S-adenosyl-i-methionine synthetase ACC 1-aminocyclopropane-1-carboxylic acid ACS 1-aminocyclopropane-1-carboxylate synthase ACO 1-aminocyclopropane-1-carboxylate oxidase Ade adenine MTA methylthioadenosine. The atoms of SAM recycled to methionine through methionine cycle are marked in red and the atoms of methionine converted to ethylene are marked in bold. For details see text.

NT564 Grady, K. L., and J. A. Bassham. 1-Aminocyclopropane-1 -carboxylic acid concentrations in shoot-forming and non-shoot forming tobacco callus NT575 cultures. Plant Physiol 1982 70 ... 

A similar 3-(2-bromoethyl) derivative has been utilized to synthesize 1-aminocyclopropane-1 -carboxylic acid by an intramolecular base-catalyzed cyclization. This was possible when position 6 was blocked by the presence of two substituents. Some unexpected stereochemical results also came up in this study (85MI2). The starting material was the piperazine-2,5-dione derived from (/ )-(+ )-2-methyl-3-phenylalanine and glycine. The bislactim ether derived from this, on treatment with butyl lithium in THF at -78°C, gave the lithio derivative. Alkylation of this with 2-haloethyl... 

The formation of ethylene is often induced by the hormone auxin (Chapter 30), which stimulates activity of the synthase that forms 1-aminocyclopropane-1-carboxylate (ACC) from S-adenosyl methionine (Eq. 14-27, step j Fig. 24-16).320a/b Although ACC has... 

Aminocyclopropane-1-carboxylic acid 4.59 a-Aminobutyric acid 10.99 3,5-Dibromotyrosine 18.43... 

Figure 3. Model of the mode of action of auxin herbicides in the induction of growth inhibition, tissue damage and senescence in dicot plant species, as illustrated for cleavers Galium aparine). ABA, abscisic acid ACC, 1 -aminocyclopropane-1 -carboxylic acid ROS, reactive oxygen species SAM, S-adenosylmethionine. Modified fiom [20,41],...

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