Aminocarboxylic acid amides

The four component condensation (Ugi reaction) " converts a mixture of substituted amine, isonitrile, aldehyde (or ketone) and carboxylic acid (Scheme 6) to a-acylaminocarboxylic acid amides (pathway a), to diacylamines (pathway b) and to a-aminocarboxylic acid amides (pathway... [Pg.405]

Aminocarboxylic acid amides from halogenocarboxylic acid esters... [Pg.117]

N-Condensed heterocyclics from o-aminocarboxylic acid amides... [Pg.415]

Platinum oxide Aminocarboxylic acid amides and aminonitriles from nitronitriles... [Pg.304]

N-Protected a-aminocarboxylic acid amides. A soln. of N-(4-methoxybenzyloxycar-bonyl)alanine in 4 1 dichloromethane/dimethylformamide treated with 1-hydroxy-benzotriazole and dicyclohexylcarbodiimide, stirred for 30 min, 25% aq. NH3 added, and stirred for 3-5 h until reaction complete (t.l.c.) - N-(4-methoxybenzyloxycar-bonyl)alanine amide. Y 83%. The method is high-yielding and racemization-free. F.e. inch Boc- and Cbz-aminoacid and dipeptide derivs. s. S.-T. Chen et al.. Synthesis 1989, 37-8 with 2-ethoxy-N-ethoxycarbonyl-l,2-dihydroquinoline and NH4HCO3 cf. S. Nozaki, I. Muramatsu, Bull. Chem. Soc. Japan 61, 2647-8 (1988). [Pg.80]

Aminocarboxylic acid amides—Michael addition s. 17, 378 Pbospbonovinylation NH NGH GHPO(OR)2... [Pg.124]

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