Aminoalkanoic acids

Such enantiomeric excesses have not been observed in analyses of the corresponding a-H-a-aminoalkanoic acids. According to the authors, the excess of the L-forms could be due to a partial photocleavage of the racemic amino acid mixture as a result of the influence of circularly polarized UV light in a presolar cloud (Cronin and Pizzarello, 2000). 

In this study, there were four linear aminoalkanoic acids [50], four different cinnamic acids, three different carbolines, three different phenanthridinones, and five different spirocyclics. The variability in the phenanthridinione series... 

Alkanoic acids with fewer than six carbon atoms Alkanedioic acids with fewer than six carbon atoms Hydroxyalkanoic acids with fewer than six carbon atoms Aminoalkanoic acids with fewer than seven carbon atoms Ammonium, sodium, and potassium salts of the above acid classes with fewer than 21 carbon atoms... 

Catalysis of D—H exchange in ketones and aldehydes by bi- and polyfunctional compounds [a>aminoalkanoic acids [82], cu-dimethylamino-alkylamines [83] and poly(ethylenimines)] has been extensively studied by Hine and coworkers as a model of various enzyme-catalysed transformations entailing analogous steps (see below). The main goal of this work lies in the determination of the steric requirements of intramolecular catalysis. Since the principal results have been recently reviewed (Hine, 1978), only a short survey will be presented here. 

Extensive research has been conducted to explore the C-28 side chain modifications of BA.30,37,38 A series of C-28 oo-aminoalkanoic acid derivatives of BA, which were first synthesised by Soler et al.,39 functions by blocking the viral entry into the host cells. Incremental chain lengthening significantly influenced the anti-HIV potency of the derivatives.4 Compounds with amide side chains between aminooctanoic acid and aminododecanoic acid (7 11 carbons between the C-28 amide moiety and the terminal carboxylic acid... 

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