7-Amino-substituted Neu5Ac derivative

Neu5CBz (entry 9) and 5-azido-5-deacetamido-Neu (entry 12) have been prepared by treatment of the corresponding 2-modified mannose derivatives with pyruvate in the presence of Neu5Ac aldolase. The C-5 azido group may be easily converted to the free amine. Synthesis of 7-amino-substituted Neu5Ac derivative has been presented [50] via azido derivative as an alternative route to the particularly difficult chemical... 

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